Return-Path: Sender: (Marvin Kaye) To: lml Date: Sat, 04 Oct 2003 22:09:40 -0400 Message-ID: X-Original-Return-Path: Received: from ms-smtp-03.tampabay.rr.com ([65.32.1.41] verified) by logan.com (CommuniGate Pro SMTP 4.1.5) with ESMTP id 2624227 for lml@lancaironline.net; Sat, 04 Oct 2003 17:01:52 -0400 Received: from tednoel (89.199.27.24.cfl.rr.com [24.27.199.89]) by ms-smtp-03.tampabay.rr.com (8.12.10/8.12.5) with SMTP id h94L1m1d017770 for ; Sat, 4 Oct 2003 17:01:48 -0400 (EDT) X-Original-Message-ID: <006d01c38aba$cabd7570$0100000a@tednoel> From: "Ted Noel" X-Original-To: "Lancair Mailing List" References: Subject: Re: Oxygen X-Original-Date: Sat, 4 Oct 2003 17:02:16 -0400 MIME-Version: 1.0 Content-Type: text/plain; charset="iso-8859-1" Content-Transfer-Encoding: 7bit X-Priority: 3 X-MSMail-Priority: Normal X-Mailer: Microsoft Outlook Express 6.00.2800.1158 X-MIMEOLE: Produced By Microsoft MimeOLE V6.00.2800.1165 > > Lack of oxygen is not sensed by the body. What happens when we feel "short > of breath" is that the body responds to excess of CO2 to tell the brain that > there is an oxygen shortage. This worked well on the African savannahs, but > where the oxygen is thin, the CO2 never gets excessive. This is only partially true. 90% of the population will get short of breath with hypoxia. I speak from experience from an occasion where I got pneumonia. I got short of breath, and nasal O2 fixed it. There is a body of research on this in the Altitude/Mountain Sickness (AMS) problem. The 10% that don't properly sense hypoxia are the ones who are particularly sensitive to AMS. My wife is one. > > In the 1930's when all this was being worked out, it was claimed that > providing the aviator with 3% CO2 (!) would allow him to fly at 17k with the > mental performance of 12k. I leave it to flight surgeons to puzzle this > out---my guess is that it is true. It is true. It acts as if you held your breath. It makes you so short of breath that you hyperventilate to reduce your CO2. In doing so, you actually reduce your CO2 enough to leave "room" for more O2. I won't bore you with the alveolar gas equation and the difference between arterial and venous CO2 on that one. In treating AMS, we give a medication that makes your blood more acid. This tricks the chemoreceptor in your brainstem into thinking that your CO2 is high. This makes people breathe faster to reduce CO2, which is the normal response to high CO2. It is also the normal response to hypoxia, but is missing in that 10%. > All said, supplemental oxygen is the proper answer. Ted Noel MD Lancair 4-P 98% N540TF