Ernest,
The latest plastic part failure that comes to mind is the plastic overflow tank on my 2007 Mazda 3. It is under something like 18-20 psi. It developed stress cracks near a seam.
I also have seen failures in plastic radiator end tanks. Of course, this could be the fault of a ham-handed mechanic, or not. Then again, I have also seen brass radiator tanks with cracks.
You made a good point about AN fittings. Hoses need to be supported in some fashion other than hanging by the fitting.
Mark