Nothing.  A little louder.  A little more air through the cabin.  Done it too many times to admit, probably because I don’t consider a serious item.  I often taxi with the canopy open until the last minute.  Sometimes forget to latch it.  I wait until the Autopilot is on before messing with it.  Sometimes it can be difficult to close in-flight.

What would happen if one takes off without latching the canopy in a Lancair 360.  Any personal experiences out there?