From Champion Automotive Service Guide:

 

Here are a couple of tips to help assure the success of changing spark plugs. The first is to remove spark plugs from aluminum cylinder heads only when the engine is cool. Since aluminum and steel expand and contract at different rates, removing spark plugs from an aluminum cylinder head while hot can actually cause thread and cylinder head damage. Before installing the spark plugs, make sure the threads are clean and in good condition. If in doubt, run a thread chaser through the plug opening in the cylinder head. Champion recommends that you do not use an anti-seize compound, since one has already been applied to the plugs at the factory. Next, install the spark plugs finger tight and, it using a taper seat spark plug, use a ratchet to rotate 1/16 of a turn. If using a gasket seat type spark plug, after installing finger tight, turn 1/4 to 5/8 of a turn. If this procedure is followed, spark plugs will not back out nor will they seize in the cylinder

 

 

From Sacramento Sky Ranch Info:

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What anti-seize should I use when installing the spark plug

Champion recommends using 2602 spark plug anti-seize. Use sparingly. Some also use C5-a copper anti-seize although we prefer the champion product which is a water based graphite.

Per Champion Aviation Service Manual: "Apply anti-seize compound sparingly to the firing end threads
but never to the first thread to prevent the material from running into the electrodes."

Proper spark plug torque depends upon using the specified anti-seize. Teledyne Continental, for example, specifically states that the their spark plug torque value is for threads lubricated with 2602 anti-seize.

Hmmmmm, more graphite........  Go figure.

Let's see, now there is enough conflicting info for the following:

Champion Automotive (and moped/motorcycle?) plugs come with an anti-seize coating?  Do others?  Well!  Then, some say use anti-seize, some say not or sparingly.  I've got my fingers in my ears now and I am saying "La la la la la la" so I can't hear anymore Pros and Cons.  I think I going to go pour myself an anti-seizure beverage and sit on the porch watching the sun set.  But I ain't never using that Permatex stuff again.

Scott