I always ask the question, Is there a mixture knob in a modern car? Long gone are the days of carburetors.
With EFI computers, they use a table (RPM vs MAP) to indicate which AFR to target. Megasquirt does an excellent job of this. Once you get your engine's volumetric efficiency table dialed in, all you have to do is change your AFR and MS will calculate your fueling to reach that AFR.